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CNS Stimulants
Generic
(Brand name)
Formulations, Usual Dose, Notes
Xanthines
Caffeine
bulletCaffeine affects sleep, particularly if taken by the end of the day. 
bulletCaffeine content:
bulletA cup of regular coffee: 100 mg. Strong coffee may contains 200 to 500 mg.
bulletA cup of tea: 50 mg
bulletA popular soda about 75 mg.
bulletHalf life of caffeine has a range of 8 to 14 hours. 
bulletCaffiene in coffee - CNN
Amphetamine Derivatives
Methyl-
phenidate
(Ritalin)
Class II
bulletTab: 5, 10, 20 mg. Half life: 4 hr, Tmax 2 hr
bulletSlow Release: 20 mg. Half life 8-10 hr, Tmax 5 hr
bulletDose: 5 mg q am, titrate up to 100 mg/day
bulletLess peripheral sympathomimetic activity.
Dextro-
amphetamine (Dexedrine)
Class II
bulletDose: 5 mg to 60 mg/day in divided dose
bulletHalf life: 10 hr, Tmax 2 hr.
Amphetamine (Adderall) Class II
bulletTab: 5, 10, 20, 30 mg tab
bulletDose: 5 mg to 60 mg/day in divided dose
bulletHalf life: 10 hr, Tmax 2 hr
Other stimulants
Modafinil (Provigil) Class IV
bulletTab: 200 mg, scored
bulletDose: 50 mg qd, up to 400 mg qd
bulletHalf life 15 hr, Tmax 2-4 hours
bulletAlpha-1 receptor agonist that has alerting properties
bulletFew side effects and may be preferable as initial treatment.
Pemoline (Cylert)
Class IV
bulletChewable tab: 37.5 mg. Tab: 18.75, 37.5, 75 mg.
bulletDose: 18.75 mg q am, titrate up to 150 mg/day
bulletHalf life: 12 hr, Tmax 2-4 hr
bullet Warning from FDA
Mazindol
(Sanorex)
Class IV
bulletTab: 1, 2 mg
bulletDose: 2-
bulletRelatively few sympathomimetic side effect
bulletAn imidazoline derivative
bulletLess effective than methylphenidate or dextroamphetamine
bulletNarcolepsy Med - Standford
bullet Neuro Medication Directory
bulletNarcolepsy - NL

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